Synthesis of Novel 2’-disubstituted Ribonucleoside Analogs

Oligonucleotides Based Approaches for Treatment of Chronic Hepatitis B

A de novo Nucleoside Synthesis: New Opportunities for Medicinal and Process Chemistry

 The Second Dimension of the Genetic Code

Triumph of Nucleic Acids

Discovery of Remdesivir and Beyond

PNAs with Double Face: Bimodal PNAs as Templates for Supramolecular Assemblies of Nucleic Acids

Design and Therapeutic Potential of Purinergic Receptor Ligands

New Backbone Chemistry Enhances the Drug-like Properties of Stereopure Oligonucleotides in Preclinical Studies

RNA Functionalization via an Expanded Genetic Alphabet

Nucleosides, Nucleotides and Human Health

Ribozyme Gene Switches for Biosensing and Regeneration Studies

A Natural Riboswitch Scaffold with Methyltransferase Activity

Novel DNA-boron Cluster Conjugates with Two Faces

Development of Sugar-modified Oligonucleotides with Higher Enzymatic Stability Than PS Oligonucleotides

Therapeutic Nucleosides and Evolution of Oligonucleotide Synthesis

In Vivo Therapeutic Genome Editing via Transient Expression of CRISPR/Cas9

Rapid Synthesis and Delivery of Antisense Oligonucleotides Enabled by Machine Learning

Enzymatic Photocaging of Nucleic Acids: A Strategy for Controlling Methyltransferase Target Sites by Light

Rapidly Advancing Transformational Therapeutic Solutions for Patients with Severe Viral Diseases

Improved Specificity of Conjugate siRNAs Through Chemical Modification

Light as a Tool for Understanding Biological Processes

Stealth Fluorescence Labeling for Live-Cell Imaging in RNA-based Therapeutics